There are certain times where you may prefer the effects of a higher THC or higher CBD strain. One example would be if you are experiencing inflammation, yet you are wanting to go about your day normally, without the psychotropic effects of THC. In this situation, a high-CBD low-THC strain can provide relief without much of an impact on mental function. In a survey of those suffering from chronic, non-cancer pain in Canada it was found that 35% of respondents reported using cannabis for pain relief.
Another study suggests that CBD in rats induced suppression of chronic inflammation and neuropathic pain through potentiating glycine receptors. Whether you live in a state where medical marijuana is not available, or you would like pain relief without any “high” feeling, CBD oil may be a good option for you.
The exact mechanisms of action are still being researched, however, CBD has been found to increase the levels of endocannabinoids in the body, specifically anandamide. It is plausible that this increase in endogenous endocannabinoids could have an impact on pain.
Choosing An Alternative To Opioid Pain Medications: Cannabis For Back Pain Management
When it comes to CBD and pain relief, research is just beginning. While there is lots of evidence for the efficacy of cannabis in relieving pain, there is much less when it comes to CBD.
A clinical endocannabinoid deficiency theory exists for multiple treatment-resistant conditions, with support from studies examining people with migraines, fibromyalgia, and intestinal pain such as IBS. This theory postulates that many of those suffering from these conditions do not produce enough endocannabinoids. The theory holds that it may be possible to treat these conditions with external cannabinoids, such as the phytocannabinoid CBD, helping these individuals find some relief.
- The study added that compared to oral cannabinoids, the effect of inhaled cannabis is more rapid, predictable, and can be titrated.
- A 2018 review, published in the Frontiers of Pharmacology, studied some of the recent findings of clinical trials to assess the efficacy of cannabinoids “to treat diseases or improve symptoms”.
- The researchers also pointed to how much thc is in CBD oil cannabidiol’s “significant analgesic, anti-inflammatory, anticonvulsant, and anxiolytic activities, without the psychoactive effect of THC”.
- CBD also interacts with some other non-endocannabinoid receptors, like GPCRs (5-HT subtypes, like 5-HT1A) to induce production and release of anandamide, thus promoting pain relief.
- Besides, sciatica patients also suffer from other issues that CBD can help with, such as improve sleep and reduce stress.
These are the two most abundant and well-studied cannabinoids in marijuana, and both have been found in numerous published studies to have pain-relieving properties in humans. While they may be the most abundant, THC and CBD are certainly not the only compounds found in cannabis that are known to exert positive effects on human health. Medical marijuana is becoming one of the most popular alternative treatments for chronic pain – this can range from pain caused by conditions such as migraines or arthritis to pain caused by injury. In fact, 94% of medicinal cannabis patients in Colorado indicated severe pain as to why they require cannabis.
Most of the ‘proof’ of CBD’s pain relieving effects come from preclinical studies, animal studies, and user reports. Activation of cannabinoid receptors has been linked to the inhibition of pain.